Effective process development towards intensified processing for gene delivery applications using Hepatitis B core Antigen (HBcAg) virus-like particles (VLPs) relies on analytical methods for the absolute quantification of HBcAg VLP proteins and bound nucleic acids.We investigated a silica spin column (SC)-based extraction procedure, including prot
Exploring Copper Oxide and Copper Sulfide for Non-Enzymatic Glucose Sensors: Current Progress and Future Directions
Millions of people worldwide are affected by diabetes, a chronic disease that continuously grows due to abnormal glucose concentration levels present in the blood.Monitoring blood glucose concentrations is therefore an essential diabetes indicator to aid in the management of the disease.Enzymatic Blunt Wraps electrochemical glucose sensors presentl
Pseudoaneurysm of the Inferior Pancreaticoduodenal Artery Due to Cholecystitis
Inferior pancreaticoduodenal artery pseudoaneurysms and aneurysms are a rare occurrence, comprising of approximately 10% of visceral artery aneurysms and pseudoaneurysms.The cause is normally due to trauma, iatrogenic or pancreatitis.We present a case of a patient re-presenting to hospital following treatment of acute cholecystitis with epigastric
Early survival factor deprivation in the olfactory epithelium enhances activity-dependent survival
The neuronal olfactory epithelium undergoes permanent renewal because of environmental aggression.This renewal is partly regulated by factors modulating the level of neuronal apoptosis.Among them, we had previously characterized endothelin as neuroprotective.In this study, we explored the effect of cell survival factor deprivation in the olfactory
Virus-specific regulatory T cells ameliorate encephalitis by repressing effector T cell functions from priming to effector stages.
Several studies have demonstrated the presence of pathogen-specific Foxp3+ CD4 Reception Desk regulatory T cells (Treg) in infected animals, but little is known about where and how these cells affect the effector T cell responses and whether they are more suppressive than bulk Treg populations.We recently showed the presence of both epitope M133-sp